Which symptom indicates an acute increase in calcium levels in the body?

An acute increase in calcium levels in the body, known as hypercalcemia, can lead to a variety of symptoms affecting multiple systems. Each of the listed symptoms contributes to a clinical picture that can be associated with hypercalcemia.

Fatigue is a common symptom experienced by individuals with elevated calcium levels, often due to the effects of hypercalcemia on muscle and nerve function, leading to general malaise and reduced energy levels.

Psychiatric changes, such as confusion, depression, or altered mental status, can also occur in the context of hypercalcemia. High calcium levels affect neurotransmitter release and neuronal excitability, which can impact mood and cognitive function.

Cardiac arrhythmias are significant because hypercalcemia can alter the electrical conduction system of the heart. Elevated calcium levels can lead to prolonged QT intervals, increased contractility, and disrupt normal heart rhythm, resulting in arrhythmias.

Since all three symptoms—fatigue, psychiatric changes, and cardiac arrhythmias—can manifest in the setting of acute hypercalcemia, the correct choice reflects the comprehensive nature of symptomatology associated with this condition. Therefore, recognizing these symptoms as indicative of elevated calcium levels is crucial for prompt diagnosis and management.