Which of the following agents is often used to manage acute mania?

The management of acute mania typically involves the use of antipsychotic medications, which are effective in rapidly stabilizing mood and alleviating manic symptoms. Antipsychotics work by blocking dopamine receptors in the brain, which can help reduce the hyperactivity, agitation, and psychotic features that may accompany acute manic episodes. These agents can provide quick relief and are often preferred in acute settings due to their rapid onset of action.

Lithium, while a cornerstone treatment for bipolar disorder, is generally used for long-term management rather than for immediate control of acute mania. Its therapeutic effects take time to establish, and it requires careful monitoring of serum levels and potential side effects.

Beta-blockers and corticosteroids do not directly address the core symptoms of mania. Beta-blockers may be used adjunctively for physical symptoms like anxiety and tremors, while corticosteroids can potentially exacerbate mood symptoms rather than providing relief.

Therefore, antipsychotics are the first-line agents for effectively managing acute manic episodes in patients with bipolar disorder.