Which condition is NOT commonly associated with Graves' disease?

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Graves' disease is an autoimmune hyperthyroid condition characterized by several hallmark features. One of the most clinically distinctive manifestations is exophthalmos, an abnormal protrusion of the eyeballs, which results from inflammation and swelling of the eye tissues. Pretibial myxedema is another condition associated with Graves' disease, involving thickening and induration of the skin over the shins due to accumulation of glycosaminoglycans. A goiter, or enlargement of the thyroid gland, is also a common finding due to hyperplasia of the follicular cells stimulated by thyroid-stimulating immunoglobulins.

In contrast, hyperthyroid myopathy is not as prominently associated with Graves' disease when compared to other conditions. While muscle weakness can occur in individuals with hyperthyroidism, and specifically with Graves' disease, it is not a defining or characteristic symptom of the disorder. Hyperthyroid myopathy can occur in the context of any significant hyperthyroid state and is not specific to Graves' disease, making it less commonly recognized compared to the other classic manifestations. Thus, identifying the most characteristic associations of Graves' disease helps in understanding its distinct clinical picture.

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