What is a known precipitant of hemolytic crisis in patients with G6PD deficiency?

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Fava beans are a known precipitant of hemolytic crisis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to their content of vicine and convicine, which are compounds that can induce oxidative stress. In G6PD deficiency, the enzyme responsible for protecting red blood cells from oxidative damage is deficient, making these cells more susceptible to hemolysis when exposed to certain oxidative agents, such as those found in fava beans. This hemolytic response leads to a rapid breakdown of red blood cells, resulting in anemia and other associated symptoms.

The other options, while they may influence overall health and could potentially contribute to other complications, do not specifically trigger hemolytic crises in the same way that fava beans do for G6PD-deficient individuals. Recognizing the role of fava beans in this particular condition is important for patient management and dietary counseling for those affected by G6PD deficiency.

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